Buy Restoril (Temazepam) online

Description

Indications and Dosage. Buy Restoril online, temazepam for sale in Australia Oral Short-term management of insomnia Adult: 7.5-30 mg at bedtime for 7-10 days. Max: 40 mg. Elderly: 5 mg at bedtime. May be increased to 10-20 mg in severe cases. Oral Premedication in surgery Adult: 20-40 mg, 30 min to 1 hr before the procedure. Elderly: 10-20 mg, 1 hr before the procedure. Buy Restoril online, temazepam for sale in Australia Renal Impairment Short-term management of insomnia: 5 mg at bedtime. May be increased to 10-20 mg in severe cases. Hepatic Impairment Short-term management of insomnia: 5 mg at bedtime. May be increased to 10-20 mg in severe cases. Severe: Contraindicated. Premedication in surgery: Severe: Contraindicated. Administration May be taken with or without food. Contraindications Acute pulmonary insufficiency, resp depression, sleep apnoea, obsessional states, myasthenia gravis, severe hepatic impairment. Pregnancy. Special Precautions Patient w/ severe depression, chronic pulmonary insufficiency, personality disorders, history of alcohol or drug addiction. Avoid abrupt withdrawal. Renal and hepatic impairment. Elderly or debilitated patient. Lactation. Buy Restoril online, temazepam for sale in Australia Adverse Reactions Complex behaviour (e.g. sleep-driving, making phone calls, preparing and eating food). Dyspnoea, nausea and vomiting, throat closing, anterograde amnesia, agitation, restlessness, irritability, excitement, aggressiveness, rage, delusions, confusion, nightmares, psychoses, hallucinations, nervousness, dizziness, drowsiness, fatigue, headache, lethargy, hangover, anxiety, depression, euphoria, ataxia, anorexia, tremor and backache. Potentially Fatal: Angioedema involving glottis, tongue or larynx. Pregnancy Category (US FDA) PO: X Patient Counseling Information May impair ability to perform tasks that require alertness (e.g. driving or operating machinery). Monitoring Parameters Monitor resp and CV status. Buy Restoril online, temazepam for sale in Australia Overdosage Symptoms: Somnolence, confusion, coma, reduced or absent reflexes, resp depression, and hypotension. Management: Supportive and symptomatic treatment. Empty stomach by vomiting or gastric lavage. Treat hypotension w/ IV pressor agents. IV fluids should be given to induce diuresis. Flumazenil may be used for the complete or partial reversal of the sedative effects but there is a risk of seizure esp in long-term benzodiazepine users and in cyclic antidepressant overdose. Drug Interactions May enhance CNS depressant effect w/ Na oxybate, antipsychotics , tranquilisers, neuroleptics, antidepressants , hypnotics, anaesth, analgesics, sedative antihistamines, barbiturates. Effect may be reduced w/ theophylline. Buy Restoril online, temazepam for sale in Australia Food Interaction May enhance sedative effect w/ alcohol. Action Description: Temazepam is a short-acting benzodiazepine w/ anxiolytic, hypnotic/sedative, muscle relaxant properties. It increases neuronal membrane permeability to Cl ions by binding to stereospecific benzodiazepine receptors on the postsynaptic GABA neuron w/in the CNS and enhancing the GABA inhibitory effects resulting in hyperpolarisation and stabilisation. Buy Restoril online, temazepam for sale in Australia Pharmacokinetics: Absorption: Readily absorbed from the GI tract. Time to peak plasma concentration: 1.2-1.6 hr. Distribution: Enters breast milk. Volume of distribution: 1.4 L/kg. Plasma protein binding: Approx 96%. Metabolism: Minimal first-pass metabolism (8%). Completely metabolised through conjugation to inactive metabolite. Excretion: Via urine (80-90% as inactive metabolites). Elimination half-life: Approx 8-15 hr. Storage Store at ≤25°C. Protect from light.